Laboratory Information

Organic Functional Design Lab

  • Undergraduate
  • Graduate
Field of Study
Organic Functional Design
Keywords
Precision Synthesis, Photofuncitonal Chemistry, Functional Polymer Materials, Main-Group Element, Biofunctional Engineering
URL
https://sites.google.com/g.ecc.u-tokyo.ac.jp/organic-functional-design-lab

MEMBERS

  • Hiroshi Masai Associate Professor
  • Taichi Koike Assistant Professor

Recent Publications

Research

Exploring new science by creating novel molecules and functions: Our research group focuses on developing unprecedented reactions, molecules, and functions by integrating new elements into innovative molecular structures. Through the power of molecules, we aim to realize novel reactions and functions that were previously thought impossible, overcoming various academic and societal challenges.

One-Shot Molecular Editing Methods :

To create novel molecules with new functions, we develop highly reactive reagents for rapidly incorporating target elements even into stable compounds. The development of synthetic methodology paves the way for advanced organic materials, such as high-performance organic batteries and photoredox catalysts.

Synergistic Stimulus-Responsive Chemical Reaction :

We develop a new class of organic reaction systems that proceed only under the simultaneous action of multiple stimuli, rather than relying on conventional reactions triggered by a single stimulus. By precise design of molecular response, we aim to establish “synergistic reactivity” as a brand new concept for developing control methods of artificial materials and biomaterials.

Creation of Materials with Conflicting Properties :

Materials often exhibit inherent trade-offs between conflicting properties. For example, durable materials are typically difficult to degrade, while easily degradable materials lack long-term usability. However, the synergistic action of two stimuli enables easy degradation of highly durable materials. We aim to address contradictory challenges in material science by precisely designed molecules.

Control of Biological Phenomena by Artificial Materials :

We develop artificially designed organic molecules and supramolecules to achieve precise control of biological functions and phenomena and to create biomaterials with unprecedented functions not found in nature. Through experimental, simulation, and machine learning-based screening and structural optimization, we will prepare a series of unique molecules that can be used in all kinds of bio-applications.